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Linzolid 600 IV Infusion 300ml
Linzolid IV is an effective antibiotic for treating severe bacterial infections but should be used cautiously, especially during pregnancy, breastfeeding, and in patients with kidney or liver disease.
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✅ Description:
Linzolid 600 IV Infusion
- Infections caused by Vancomycin-Resistant Enterococcus faecium, including cases with concomitant bacteremia.
- Nosocomial pneumonia caused by Staphylococcus aureus (methicillin-susceptible and -resistant strains) or Streptococcus pneumoniae, including multi-drug resistant strains. Combination treatment may be necessary if Gram-negative organisms are present.
- Infections of the skin and skin structure caused by Staphylococcus aureus (methicillin-susceptible and methicillin-resistant strains), Streptococcus pyogenes, or Streptococcus agalactiae, including diabetic foot infections (without accompanying osteomyelitis).
- Staphylococcus aureus (methicillin-susceptible only) or Streptococcus pyogenes infections of the skin and skin structure.
- Community-acquired pneumonia caused by Streptococcus pneumoniae (including multi-drug resistant strains), including cases with concomitant bacteremia or Staphylococcus aureus (methicillin-susceptible strains only).
Safety Advices
Alcohol
UNSAFE
Unsafe to consume with Linzolid 600 IV Infusion.
Pregnancy
CONSULT YOUR DOCTOR
Consult your doctor before use as it may be unsafe.
Breastfeeding
CONSULT YOUR DOCTOR
Consult your doctor before use as it may be unsafe for the baby.
Driving
UNSAFE
Unsafe as it may decrease alertness or cause dizziness.
Kidney
CONSULT YOUR DOCTOR
Safe if prescribed; no dose adjustment needed.
Liver
CONSULT YOUR DOCTOR
Use with caution in severe liver disease; dose adjustment may be necessary.
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✔️ Uses of Linzolid 600 IV Infusion
Linzolid 600 IV Infusion is an antibiotic used to treat severe bacterial infections of the lungs, skin, and soft tissues.
✔️ How does Linzolid 600 IV Infusion work?
It inhibits bacterial protein synthesis, leading to bacterial growth inhibition.
✔️ Side Effects of Linzolid 600 IV Infusion
- Common side effects include diarrhea, headache, nausea, oral and vaginal moniliasis, hypertension, and dyspepsia.
✔️ Quick Suggestions:
- Take Linzolid 600 IV Infusion with food to avoid stomach upset.
- Finish the full course even if you feel better.
- Inform your doctor if you experience persistent diarrhea or blood in stools.
- Avoid tyramine-rich foods like cheese, smoked fish, and certain beers.
- Seek medical attention if you develop fever, shortness of breath, or vision changes.
✔️ Pharmacology
- Linezolid is a synthetic antibacterial drug belonging to the oxazolidinones class.
- It inhibits bacterial protein synthesis selectively by binding to the 23S ribosomal RNA of the bacterial ribosome's 50S subunit, preventing the development of a functional 70S initiation complex.
- Linezolid is bacteriostatic against enterococci and staphylococci and bactericidal against most streptococci strains.
✔️ Dosage of Linzolid 600 IV Infusion
- The dosage varies based on age, type of infection, and patient condition.
- Patients may be switched from parenteral to oral formulation when clinically indicated.
- Dosage ranges from 10 mg/kg to 600 mg b.i.d or t.i.d, depending on the indication and patient's age.
- Recommended treatment duration ranges from 10 to 28 consecutive days.
✔️ Administration of Linzolid 600 IV Infusion
- Oral suspension should be reconstituted with boiled and cooled water.
- Intravenous infusion should be administered over 30 to 120 minutes.
- The suspension should be stored in a cool, dry place and used within 21 days after the constitution.
✔️ Interaction of Linzolid 600 IV Infusion
- Linezolid is a reversible and nonselective monoamine oxidase inhibitor.
- It may interact with adrenergic and serotoninergic agents, requiring dosage adjustments and careful monitoring.
✔️ Contraindications of Linzolid 600 IV Infusion
- Linezolid formulations should not be used in patients with hypersensitivity to Linezolid or its components.
- Contraindicated in patients taking medications that inhibit monoamine oxidases A or B within two weeks.
- Avoid in patients with uncontrolled hypertension, pheochromocytoma, thyrotoxicosis, or carcinoid syndrome.
✔️ Pregnancy & Lactation
- Use during pregnancy (Category C) only if potential benefits outweigh the risks.
- Linezolid is not known to be excreted in human milk, but caution is advised during lactation.
✔️ Precautions & Warnings
- Monitor patients for nausea, vomiting, acidosis, low bicarbonate levels, and signs of serotonin syndrome.
- Patients with a history of seizures or risk factors should be closely monitored for convulsions.
✔️ Storage Conditions
Store Linezolid formulations at room temperature and protect them from freezing.
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